HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: MED28 (Q9H204)
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Gene: MED28

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16964398
Identification Methods	affinity chromatography technology, peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 178
+	Hs
		789091 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		412351 FYN_HUMAN (556-721): 1.61e-31: 131: 20.69		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		986396 BTK_HUMAN (551-727): 5.38e-31: 131: 20.65		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		411851 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		789008 TEC_HUMAN (392-727): 6.13e-31: 130: 14.80		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		433471 YES_HUMAN (556-728): 9.82e-31: 129: 19.34		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		442883 HCK_HUMAN (551-724): 1.01e-30: 128: 22.53		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		523146 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Mm
		763402 FYN_MOUSE (556-721): 1.46e-31: 131: 20.69		MED28_MOUSE (1-178): 8.45e-99: 284: 94.38
+	Hs
		655464 P85A_HUMAN (606-721): 5.69e-21: 100: 28.81		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		924856 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00