Interactor 1: MED30 (Q96HR3)
Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)
Gene: MED30

Interactor 2: MED28 (Q9H204)
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Gene: MED28

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 24981860, 24882805, 15175163, 32296183, 33961781, 35271311, 20133760, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, validated two hybrid, tandem affinity purification, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med28~Med30
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0035019 - somatic stem cell population maintenance
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 178
Hs

1 178
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024