Interactor 1: MED30 (Q96HR3)
Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)
Gene: MED30

Interactor 2: MED20 (Q9H944)
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)
Gene: MED20

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.737

The method score is based on:

Property Details
Experiments 25281560, 24981860, 33961781, 35271311, 24882805, 15989967
Identification Methods proximity labelling technology, affinity chromatography technology, tandem affinity purification, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 178
Hs

1 212
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024