HitPredict

Interactor 1: HES6 (Q96HZ4)
Transcription cofactor HES-6 (C-HAIRY1) (Class B basic helix-loop-helix protein 41) (bHLHb41) (Hairy and enhancer of split 6)
Gene: HES6

Interactor 2: HES6 (Q96HZ4)
Transcription cofactor HES-6 (C-HAIRY1) (Class B basic helix-loop-helix protein 41) (bHLHb41) (Hairy and enhancer of split 6)
Gene: HES6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17868320
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 12 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 224
Hs

1 224
+ Dr
+ Hs
+ Mm
+ Hs
+ Gg
+ Gg
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024