HitPredict

Interactor 1: THOC3 (Q96J01)
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)
Gene: THOC3

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 351 Hs			1 2517
+	Hs
		903450 WDR5_HUMAN (4-251): 1.76e-70: 224: 18.75		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		817868 WDR5_HUMAN (4-251): 1.76e-70: 224: 18.75		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		903155 WDR5_HUMAN (4-251): 1.76e-70: 224: 18.75		SRY_HUMAN (1065-1189): 2.77e-37: 142: 25.60
+	Hs
		818441 TBL1R_HUMAN (4-172): 2.09e-38: 145: 17.42		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		1142008 TBL1R_MOUSE (4-172): 1.53e-38: 145: 17.42		Q60I23_MOUSE (1102-1308): 2.84e-56: 201: 27.40
+	Hs
		1288258 SNR40_HUMAN (7-250): 1.12e-59: 197: 13.33		MINT_HUMAN (730-2515): 3e-28: 127: 9.45
+	Hs
		196970 PRP4_HUMAN (210-349): 1.27e-26: 111: 16.78		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		1056932 SNR40_HUMAN (7-250): 1.12e-59: 197: 13.33		MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30
+	Hs
		903374 WDR5_HUMAN (4-251): 1.76e-70: 224: 18.75		KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57
+	Mm
		903669 WDR5_MOUSE (4-251): 1.76e-70: 224: 18.75		KMT2C_MOUSE (641-2516): 2.93e-09: 65.3: 9.74
+	Hs
		1302927 NLE1_HUMAN (215-351): 2.9e-41: 152: 22.22		MINT_HUMAN (730-2515): 3e-28: 127: 9.45
+	Hs
		1288413 SNR40_HUMAN (7-250): 1.12e-59: 197: 13.33		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		1288394 SNR40_HUMAN (7-250): 1.12e-59: 197: 13.33		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		1264784 SNR40_HUMAN (7-250): 1.12e-59: 197: 13.33		TITIN_HUMAN (609-1544): 3.51e-09: 65.2: 9.85
+	Ce
		1089274 WDR51_CAEEL (2-168): 3.73e-32: 125: 15.12		SOX2_CAEEL (1065-1195): 3.01e-30: 124: 30.53
+	Hs
		1346974 NLE1_HUMAN (215-351): 2.9e-41: 152: 22.22		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		1346970 NLE1_HUMAN (215-351): 2.9e-41: 152: 22.22		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		1281391 FBXW7_HUMAN (251-351): 8.37e-17: 83.5: 15.53		PRR36_HUMAN (293-1379): 6.9e-26: 119: 11.48
+	Hs
		818834 FBXW7_HUMAN (251-351): 8.37e-17: 83.5: 15.53		SOX9_HUMAN (1031-1201): 1.04e-24: 112: 23.08
+	Hs
		793042 LIS1_HUMAN (260-351): 5.98e-21: 94.7: 20.43		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34