Interactor 1: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Interactor 2: DISC1 (Q9NRI5)
Disrupted in schizophrenia 1 protein
Gene: DISC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 29961565
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 903
Hs

1 854
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024