Interactor 1: PIWL1 (Q96J94)
Piwi-like protein 1 (EC 3.1.26.-)
Gene: PIWIL1
Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 1.00 | 0.766 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14749716 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ArgoL1~PAZ, PAZ~PAZ, PAZ~Ribonuclease_3, PAZ~Piwi |
| Common GO terms | GO:0004521 - RNA endonuclease activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0046872 - metal ion binding |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
