HitPredict

Interactor 1: HIC2 (Q96JB3)
Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30)
Gene: HIC2

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 615 Hs			1 669
+	Hs
		781326 BCL6_HUMAN (23-614): 5.08e-117: 365: 21.93		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		1068608 ZN721_HUMAN (312-614): 6.45e-82: 278: 19.23		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		549220 ZN250_HUMAN (107-385): 5.86e-27: 117: 9.57		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		149023 ZN695_HUMAN (403-614): 8.82e-65: 223: 25.47		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		549242 ZN250_HUMAN (107-385): 5.86e-27: 117: 9.57		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		563800 ZNF3_HUMAN (272-420): 4.02e-19: 92.5: 12.67		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		563788 ZNF3_HUMAN (272-420): 4.02e-19: 92.5: 12.67		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		149395 ZN107_HUMAN (65-220): 6.23e-19: 93.2: 10.90		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149092 ZN431_HUMAN (106-353): 1.83e-15: 81.7: 8.07		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36