Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: CIKS (O43734)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)
Gene: TRAF3IP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 21822258, 30892082
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0023019 - signal transduction involved in regulation of gene expression
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0048255 - mRNA stabilization
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 557
Hs

1 574
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Last updated: 15 Jul 2024