Interactor 1: VCIP1 (Q96JH7)
Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein)
Gene: VCPIP1

Interactor 2: SPRTN (Q9H040)
DNA-dependent metalloprotease SPRTN (EC 3.4.24.-) (DNA damage protein targeting VCP) (DVC1) (Protein with SprT-like domain at the N terminus) (Spartan)
Gene: SPRTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.55 0.598

The method score is based on:

Property Details
Experiments 32649882, 22902628
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0006508 - proteolysis
GO:0006974 - DNA damage response
GO:0106300 - protein-DNA covalent cross-linking repair
Homologous interactions 0

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Last updated: 15 Jul 2024