HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: CD27 (P26842)
CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
Gene: CD27

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	9582383
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 260
+	Hs
		129532 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR5_HUMAN (6-256): 9.82e-60: 192: 22.52
+	Mm
		936208 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR14_MOUSE (9-250): 4.75e-49: 164: 17.32
+	Mm
		192584 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00
+	Hs
		129607 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR11_HUMAN (17-214): 2.77e-39: 145: 19.09
+	Hs
		129536 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR3_HUMAN (4-183): 4.01e-38: 139: 20.69
+	Mm
		648958 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR5_MOUSE (6-256): 2.05e-59: 191: 20.77
+	Hs
		129584 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR14_HUMAN (6-215): 9.79e-34: 125: 19.55
+	Hs
		129526 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR16_HUMAN (17-183): 4e-31: 121: 19.88
+	Mm
		838552 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR3_MOUSE (30-183): 2.34e-31: 121: 22.29
+	Hs
		129534 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR8_HUMAN (28-190): 1.32e-22: 98.4: 14.54
+	Mm
		192587 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR11_MOUSE (4-211): 3.81e-45: 161: 20.00
+	Hs
		129538 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR4_HUMAN (30-183): 3.79e-21: 91.4: 20.38
+	Hs
		129553 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR9_HUMAN (40-183): 6.75e-21: 90.3: 20.00
+	Hs
		584394 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1A_HUMAN (27-260): 1.96e-40: 146: 20.49
+	Hs
		129599 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR19_HUMAN (9-155): 2.03e-12: 68.3: 20.78
+	Hs
		591320 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1B_HUMAN (13-174): 1.53e-36: 136: 19.77
+	Mm
		838553 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR3_MOUSE (30-183): 2.34e-31: 121: 22.29
+	Hs
		436620 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR16_HUMAN (17-183): 4e-31: 121: 19.88
+	Mm
		812913 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR4_MOUSE (30-183): 2.63e-23: 97.2: 23.57
+	Mm
		591448 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR9_MOUSE (37-193): 8.01e-21: 90.3: 20.89