HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TANK (Q92844)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	26779844, 30561431, 33961781
Identification Methods	unspecified method, affinity chromatography technology, virotrap, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 425
+	Hs
		1024723 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TANK_HUMAN (1-425): 0: 833: 100.00
+	Mm
		936633 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TANK_MOUSE (1-425): 0: 781: 79.58
+	Hs
		1020843 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		TANK_HUMAN (1-425): 0: 833: 100.00
+	Hs
		1271787 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		TANK_HUMAN (1-425): 0: 833: 100.00
+	Mm
		761808 TRAF2_MOUSE (28-554): 5.26e-102: 318: 33.46		TANK_MOUSE (1-425): 0: 781: 79.58
+	Hs
		1023743 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		TANK_HUMAN (1-425): 0: 833: 100.00
+	Hs
		1271752 TRAF4_HUMAN (29-551): 2.98e-73: 243: 23.32		TANK_HUMAN (1-425): 0: 833: 100.00
+	Mm
		761778 TRAF1_MOUSE (156-552): 1.82e-76: 249: 30.84		TANK_MOUSE (1-425): 0: 781: 79.58
+	Hs
		1271759 RNF41_HUMAN (30-156): 3.89e-25: 108: 27.82		TANK_HUMAN (1-425): 0: 833: 100.00