HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31666375, 11279055
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 1102
+	Hs
		1024726 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1020848 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273989 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1023747 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273839 TRAF4_HUMAN (29-551): 2.98e-73: 243: 23.32		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273788 TRI11_HUMAN (34-468): 2.85e-72: 240: 13.01		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		536961 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1223388 TRI22_HUMAN (38-468): 2.92e-62: 214: 10.70		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273967 TRI35_HUMAN (25-469): 6.8e-57: 200: 11.82		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273855 TRIM8_HUMAN (40-403): 3.18e-43: 164: 13.72		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273857 TRI31_HUMAN (34-365): 4.69e-41: 155: 16.42		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1024738 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		UBP47_HUMAN (208-737): 3.48e-107: 368: 26.62
+	Hs
		1024693 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05
+	Hs
		1020772 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		1020743 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05
+	Hs
		1295925 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		UBP47_HUMAN (208-737): 3.48e-107: 368: 26.62
+	Mm
		936251 TRAF6_MOUSE (21-551): 2.76e-83: 271: 22.20		UBP47_MOUSE (167-737): 1.59e-103: 357: 24.61
+	Hs
		1173894 TRI35_HUMAN (25-469): 6.8e-57: 200: 11.82		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		1295898 TRI31_HUMAN (34-365): 4.69e-41: 155: 16.42		UBP47_HUMAN (208-737): 3.48e-107: 368: 26.62
+	Hs
		1019375 TRI26_HUMAN (39-383): 1.12e-44: 167: 13.92		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13