HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 669
+	Mm
		761834 TRAF2_MOUSE (28-554): 5.26e-102: 318: 33.46		LZTS2_MOUSE (1-669): 1.18e-58: 211: 90.16
+	Hs
		1020893 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		1111925 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		SMCA4_MOUSE (18-526): 1.74e-30: 130: 12.69
+	Hs
		537021 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		728474 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53
+	Hs
		1020668 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		584960 RO52_HUMAN (32-468): 2.83e-73: 243: 11.19		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		584968 RO52_HUMAN (32-468): 2.83e-73: 243: 11.19		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		584985 RO52_HUMAN (32-468): 2.83e-73: 243: 11.19		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		536877 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Dm
		1280285 Q960H6_DROME (124-550): 9.53e-66: 222: 20.05		Q9VB71_DROME (338-655): 3.48e-12: 72: 20.06
+	Dm
		1361822 Q9VXG5_DROME (153-550): 5.24e-61: 208: 19.28		Q9VB71_DROME (338-655): 3.48e-12: 72: 20.06
+	Hs
		149258 TRIM4_HUMAN (36-468): 9.58e-60: 208: 11.30		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1078905 TRIM8_HUMAN (40-403): 3.18e-43: 164: 13.72		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		1357714 TRI35_HUMAN (25-469): 6.8e-57: 200: 11.82		MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44
+	Hs
		1052780 TRI25_HUMAN (38-387): 1.04e-43: 166: 15.43		MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02
+	Hs
		165781 RNF41_HUMAN (30-156): 3.89e-25: 108: 27.82		N4BP3_HUMAN (17-640): 5.23e-34: 139: 27.16
+	Hs
		1012561 TRAF7_HUMAN (17-297): 2.01e-44: 168: 20.81		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		1019301 TRI26_HUMAN (39-383): 1.12e-44: 167: 13.92		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		725238 TRI31_HUMAN (34-365): 4.69e-41: 155: 16.42		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79