HitPredict

Interactor 1: ASPP1 (Q96KQ4)
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Gene: PPP1R13B

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1090 Hs			1 669
+	Hs
		1145885 ASPP1_HUMAN (1-1090): 1.25e-150: 479: 100.00		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		1043766 ASPP2_HUMAN (1-1090): 2e-141: 456: 46.13		EP15R_HUMAN (483-668): 6.69e-11: 67.8: 12.90
+	Hs
		1043659 ASPP2_HUMAN (1-1090): 2e-141: 456: 46.13		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		1043678 ASPP2_HUMAN (1-1090): 2e-141: 456: 46.13		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		847028 DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		1127245 TGO1_HUMAN (10-584): 5.07e-78: 283: 16.35		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		1051379 DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		1137887 DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68
+	Hs
		725205 DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		1237564 ANR44_HUMAN (750-1058): 2.63e-46: 183: 14.11		MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24
+	Mm
		1161349 TNKS1_MOUSE (664-1012): 6.88e-41: 166: 11.62		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Hs
		1294328 PP16A_HUMAN (901-999): 6.07e-19: 93.8: 35.35		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		846801 ANR54_HUMAN (850-1007): 1.3e-40: 153: 27.95		SMCA2_HUMAN (18-531): 1.58e-34: 143: 13.60
+	Hs
		166927 ANR28_HUMAN (709-1086): 2.22e-47: 186: 12.88		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		1078843 ANR54_HUMAN (850-1007): 1.3e-40: 153: 27.95		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		1051366 ANR52_HUMAN (751-1080): 6.18e-45: 178: 14.04		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		166947 ANR28_HUMAN (709-1086): 2.22e-47: 186: 12.88		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		225152 MYPT2_HUMAN (857-997): 1.8e-38: 158: 32.62		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		1068614 CTTB2_HUMAN (541-1085): 6.61e-36: 150: 13.35		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		149481 PCLO_HUMAN (299-894): 8.38e-16: 85.2: 11.99		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36