HitPredict

Interactor 1: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Interactor 2: PEAK1 (Q9H792)
Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)
Gene: PEAK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 236 Hs			1 1746
+	Hs
		1183555 RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		951343 RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		925619 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		892599 RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		564687 RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		545621 RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		900910 RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		894437 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		568715 RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		681775 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		AKT1_HUMAN (1362-1695): 4.43e-91: 307: 15.07
+	Hs
		568619 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		568611 RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		568605 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		568794 RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		1315495 RAB1B_HUMAN (25-234): 1.46e-73: 223: 21.03		PINK1_HUMAN (1357-1669): 2.87e-73: 258: 23.64
+	Hs
		900861 RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62		PINK1_HUMAN (1357-1669): 2.87e-73: 258: 23.64
+	Hs
		616691 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		KS6B1_HUMAN (1453-1683): 8.42e-45: 173: 16.17
+	Ce
		136793 RAC1_CAEEL (32-216): 2.66e-75: 227: 52.43		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80
+	Ce
		104464 G5EBV3_CAEEL (26-216): 8.34e-73: 221: 51.31		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80
+	Ce
		136794 CDC42_CAEEL (32-215): 8.56e-67: 206: 54.89		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80