HitPredict

Interactor 1: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 1771
+	Hs
		1183607 RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		951454 RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		925723 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		892676 RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		564734 RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		545696 RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		901042 RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		894580 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		1330985 RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		1021421 RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		950953 RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		925238 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		900423 RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		893947 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		925204 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		ANK2_HUMAN (3-233): 5.93e-53: 208: 25.11
+	Mm
		71299 RAB13_MOUSE (25-236): 2.24e-78: 235: 24.19		ANR44_MOUSE (1-103): 1.84e-18: 94.4: 19.63