HitPredict

Interactor 1: NSD1 (Q96L73)
Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.357) (Androgen receptor coactivator 267 kDa protein) (Androgen receptor-associated protein of 267 kDa) (H3-K36-HMTase) (Lysine N-methyltransferase 3B) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein)
Gene: NSD1

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	unassigned3713
Identification Methods	phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2696 Hs			1 482
+	Hs
		1030425 NSD1_HUMAN (1-2696): 0: 3408: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030265 EZH2_HUMAN (1883-2067): 7.8e-59: 220: 29.80		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1049500 EZH1_HUMAN (1890-2067): 8.95e-60: 223: 30.89		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		1049466 EZH2_HUMAN (1883-2067): 7.8e-59: 220: 29.80		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		1080195 EZH2_HUMAN (1883-2067): 7.8e-59: 220: 29.80		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63