HitPredict

Interactor 1: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 3159 Hs			1 400
+	Hs
		229488 SMCA5_HUMAN (970-1548): 0: 629: 21.71		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		229338 SMCA5_HUMAN (970-1548): 0: 629: 21.71		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1326747 CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		125173 SMCA1_HUMAN (938-1627): 0: 623: 19.83		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		808948 CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Dm
		631298 BRM_DROME (1527-2267): 3.24e-149: 512: 14.69		YAP1_DROME (17-223): 5.05e-46: 164: 22.80
+	Hs
		1170084 SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		847075 SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		808716 SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808408 SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808409 SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Dm
		1364143 INO80_DROME (1887-2145): 3.88e-75: 281: 26.92		NEDD4_DROME (4-326): 2.7e-13: 73.9: 9.66
+	Hs
		125259 SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		125260 SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		846873 SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65		SMUF2_HUMAN (156-326): 4.16e-25: 109: 11.92
+	Hs
		847097 SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09