Interactor 1: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 28514442, 28561026, 33961781, 35271311, 29028833, 11509179, 37071682, 16601686
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~TIP49, SNF2-rel_dom~TIP49
Common GO terms GO:0000786 - nucleosome
GO:0000812 - Swr1 complex
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 3159
Hs

1 463
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024