HitPredict

Interactor 1: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PDZ_5
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 817
+	Hs
		876469 SNX27_HUMAN (1-541): 0: 625: 100.00		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Mm
		1112558 SNX27_MOUSE (1-541): 0: 621: 98.52		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Rn
		192507 NEB1_RAT (40-375): 5.28e-41: 160: 14.43		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Mm
		1163957 Q7TN74_MOUSE (40-375): 2.98e-41: 161: 14.43		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		1163949 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		936181 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG3_MOUSE (154-707): 1.11e-45: 178: 12.34
+	Mm
		1163969 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG1_MOUSE (258-621): 4.08e-36: 148: 18.13
+	Hs
		1168358 PZRN4_HUMAN (30-303): 9.57e-36: 144: 16.61		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		876536 NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Hs
		1252551 PZRN3_HUMAN (21-281): 3.18e-33: 136: 17.10		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Mm
		1164021 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG2_MOUSE (419-621): 1.35e-28: 125: 21.18
+	Mm
		1143348 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Rn
		1144361 SHAN1_RAT (43-183): 5e-32: 133: 30.28		DLG2_RAT (419-621): 1.1e-28: 125: 21.18
+	Mm
		88371 SHAN1_MOUSE (43-183): 5.48e-32: 133: 30.28		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		942404 SHAN1_HUMAN (43-169): 7.26e-32: 133: 30.71		DLG4_HUMAN (438-714): 5.19e-28: 122: 16.38
+	Rn
		677807 SHAN1_RAT (43-183): 5e-32: 133: 30.28		DLG4_RAT (438-714): 1e-27: 121: 16.38
+	Hs
		942399 SHAN2_HUMAN (43-147): 7.14e-29: 124: 38.10		DLG4_HUMAN (438-714): 5.19e-28: 122: 16.38
+	Rn
		957065 SHAN1_RAT (43-183): 5e-32: 133: 30.28		GRIP1_RAT (165-625): 9.79e-12: 71.2: 11.94