HitPredict

Interactor 1: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 1190
+	Hs
		990916 SNX27_HUMAN (1-541): 0: 625: 100.00		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Hs
		1301995 NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Mm
		1112558 SNX27_MOUSE (1-541): 0: 621: 98.52		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Rn
		1144072 GRASP_RAT (7-172): 5.89e-30: 123: 24.86		CSKP_RAT (229-890): 1.15e-93: 323: 15.72
+	Hs
		158254 LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Hs
		158282 LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65		MPP2_HUMAN (428-890): 1.51e-90: 305: 16.35
+	Mm
		1143348 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Rn
		677807 SHAN1_RAT (43-183): 5e-32: 133: 30.28		DLG4_RAT (3-423): 1.74e-52: 199: 18.89
+	Hs
		942404 SHAN1_HUMAN (43-169): 7.26e-32: 133: 30.71		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Mm
		88371 SHAN1_MOUSE (43-183): 5.48e-32: 133: 30.28		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		942399 SHAN2_HUMAN (43-147): 7.14e-29: 124: 38.10		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Rn
		677802 GRASP_RAT (7-172): 5.89e-30: 123: 24.86		DLG4_RAT (3-423): 1.74e-52: 199: 18.89
+	Mm
		1143381 SHAN2_MOUSE (43-147): 1.26e-28: 123: 39.05		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1164021 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG2_MOUSE (8-534): 5.21e-45: 178: 15.58
+	Mm
		1163969 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG1_MOUSE (1-513): 1.74e-44: 177: 16.44
+	Hs
		158271 LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Rn
		1144361 SHAN1_RAT (43-183): 5e-32: 133: 30.28		DLG2_RAT (8-534): 1.37e-45: 179: 15.41
+	Hs
		158277 LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		158294 LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65		PALS1_HUMAN (455-886): 1.77e-39: 159: 19.67
+	Mm
		936181 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		DLG3_MOUSE (372-595): 5.97e-13: 75.5: 18.10