HitPredict

Interactor 1: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 761
+	Hs
		1050144 SNX27_HUMAN (1-541): 0: 625: 100.00		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Hs
		1066126 SNX27_HUMAN (1-541): 0: 625: 100.00		ACAP2_HUMAN (2-331): 3.4e-53: 199: 18.50
+	Hs
		166999 SNX27_HUMAN (1-541): 0: 625: 100.00		ANR28_HUMAN (52-250): 1.89e-18: 92.5: 11.06
+	Hs
		1075477 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		153960 NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Mm
		1115948 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		GIT1_MOUSE (1-761): 7.5e-170: 509: 96.62
+	Hs
		1050110 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Mm
		110605 H3BL28_MOUSE (40-375): 4.97e-42: 163: 14.43		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112600 Q7TN74_MOUSE (40-375): 2.98e-41: 161: 14.43		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112594 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		88367 SHAN1_MOUSE (43-183): 5.48e-32: 133: 30.28		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112608 SHAN2_MOUSE (43-147): 1.26e-28: 123: 39.05		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		1264864 LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95		ARAP2_HUMAN (7-223): 6.18e-51: 195: 27.15
+	Hs
		1138562 SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14		AGAP7_HUMAN (2-223): 5.98e-55: 202: 32.89
+	Mm
		1112568 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		167037 NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43		ANR28_HUMAN (52-250): 1.89e-18: 92.5: 11.06
+	Mm
		103604 NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98		ANK3_MOUSE (237-740): 1.36e-20: 99.9: 9.25
+	Hs
		167005 NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98		ANR28_HUMAN (52-250): 1.89e-18: 92.5: 11.06
+	Mm
		103600 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		ANK3_MOUSE (237-740): 1.36e-20: 99.9: 9.25
+	Mm
		1115906 SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19		ANR28_MOUSE (54-250): 3.13e-18: 91.8: 11.16