HitPredict

Interactor 1: MAGBA (Q96LZ2)
Melanoma-associated antigen B10 (MAGE-B10 antigen)
Gene: MAGEB10

Interactor 2: MAGC2 (Q9UBF1)
Melanoma-associated antigen C2 (Cancer/testis antigen 10) (CT10) (Hepatocellular carcinoma-associated antigen 587) (MAGE-C2 antigen) (MAGE-E1 antigen)
Gene: MAGEC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MAGE~MAGE
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 347 Hs			1 373
+	Hs
		796255 MAGAB_HUMAN (1-316): 7.45e-153: 438: 42.27		MAGAB_HUMAN (1-344): 5.42e-128: 376: 39.83
+	Hs
		180538 MAGA8_HUMAN (1-315): 1.17e-146: 418: 43.04		MAGB4_HUMAN (51-357): 2.14e-122: 358: 42.72
+	Hs
		180537 MAGA3_HUMAN (1-316): 1.15e-145: 415: 37.86		MAGB4_HUMAN (51-357): 2.14e-122: 358: 42.72
+	Hs
		796241 MAGAA_HUMAN (1-327): 1.81e-147: 422: 43.43		MAGBA_HUMAN (1-361): 4.35e-119: 350: 39.07
+	Hs
		795807 MAGAA_HUMAN (1-327): 1.81e-147: 422: 43.43		MAGA4_HUMAN (1-332): 2.14e-119: 349: 40.95
+	Hs
		795849 MAGAB_HUMAN (1-316): 7.45e-153: 438: 42.27		MAGA6_HUMAN (1-342): 5.53e-113: 333: 38.91
+	Hs
		180525 MAGB4_HUMAN (1-332): 5.75e-144: 412: 53.01		MAGB4_HUMAN (51-357): 2.14e-122: 358: 42.72
+	Hs
		795716 MAGA8_HUMAN (1-315): 1.17e-146: 418: 43.04		MAGA3_HUMAN (1-342): 6.5e-120: 351: 38.91
+	Hs
		795805 MAGA8_HUMAN (1-315): 1.17e-146: 418: 43.04		MAGA4_HUMAN (1-332): 2.14e-119: 349: 40.95
+	Hs
		180569 MAGB4_HUMAN (1-332): 5.75e-144: 412: 53.01		MAGBA_HUMAN (1-361): 4.35e-119: 350: 39.07
+	Hs
		796054 MAGAA_HUMAN (1-327): 1.81e-147: 422: 43.43		MAGA9_HUMAN (8-344): 1.12e-115: 340: 41.81
+	Hs
		795715 MAGA3_HUMAN (1-316): 1.15e-145: 415: 37.86		MAGA6_HUMAN (1-342): 5.53e-113: 333: 38.91
+	Hs
		180521 MAGB3_HUMAN (1-331): 1.35e-146: 419: 47.43		MAGA1_HUMAN (35-331): 1.83e-110: 327: 43.05
+	Hs
		795688 MAGA3_HUMAN (1-316): 1.15e-145: 415: 37.86		MAGA2_HUMAN (1-342): 4.66e-111: 328: 36.89
+	Hs
		180536 MAGB4_HUMAN (1-332): 5.75e-144: 412: 53.01		MAGA1_HUMAN (35-331): 1.83e-110: 327: 43.05
+	Hs
		180169 MAGB4_HUMAN (1-332): 5.75e-144: 412: 53.01		MAGB2_HUMAN (61-342): 3.21e-106: 316: 43.60