HitPredict

Interactor 1: ANR27 (Q96NW4)
Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein)
Gene: ANKRD27

Interactor 2: RB40C (Q96S21)
Ras-related protein Rab-40C (Rar-like protein) (Ras-like protein family member 8C) (SOCS box-containing protein RAR3)
Gene: RAB40C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	25661869
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_2~SOCS_box, Ras~VPS9
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 281
+	Hs
		1017279 ANR27_HUMAN (1-1050): 0: 733: 100.00		RB40B_HUMAN (1-281): 7.92e-101: 297: 78.65
+	Hs
		1263840 ANR27_HUMAN (1-1050): 0: 733: 100.00		RB40A_HUMAN (1-281): 7.41e-97: 287: 74.02
+	Mm
		1112990 ANR27_MOUSE (1-1050): 0: 705: 79.24		RB40C_MOUSE (1-281): 3.03e-96: 286: 99.29
+	Hs
		914438 RABX5_HUMAN (96-401): 2.66e-129: 403: 23.85		RB11A_HUMAN (4-229): 4.3e-87: 260: 31.72
+	Hs
		1237552 ANR44_HUMAN (98-809): 7.29e-79: 280: 12.72		RB40C_HUMAN (1-281): 8.84e-97: 287: 100.00
+	Hs
		167004 ANR28_HUMAN (86-614): 2.41e-71: 259: 18.43		RB40C_HUMAN (1-281): 8.84e-97: 287: 100.00
+	Mm
		71299 ANR44_MOUSE (98-809): 3.3e-79: 281: 13.55		RAB13_MOUSE (7-193): 3.95e-89: 265: 42.55
+	Hs
		1239498 ANR52_HUMAN (778-1039): 2.62e-43: 173: 17.94		RB40C_HUMAN (1-281): 8.84e-97: 287: 100.00
+	Mm
		1257615 ANR17_MOUSE (131-452): 3.18e-36: 151: 8.85		RB40B_MOUSE (1-281): 2.78e-99: 293: 77.58
+	Hs
		1021405 ANK3_HUMAN (10-404): 9.35e-28: 124: 7.60		RAB35_HUMAN (7-197): 1.09e-83: 251: 34.33