HitPredict

Interactor 1: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 236 Hs			1 147
+	Hs
		849413 BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919831 BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895884 BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		851874 BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		896521 BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		849400 BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919817 BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895871 BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		851864 BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		849456 BIRC6_HUMAN (1-185): 2.65e-36: 137: 20.31		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		849396 MIB2_HUMAN (37-234): 9.33e-29: 115: 19.34		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919813 MIB2_HUMAN (37-234): 9.33e-29: 115: 19.34		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	At
		715121 RGLG3_ARATH (53-234): 4.34e-24: 100: 15.61		UBC8_ARATH (1-147): 7.07e-83: 241: 80.27
+	Hs
		849387 RFFL_HUMAN (64-236): 4.82e-24: 100: 17.78		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	At
		1247333 RGLG3_ARATH (53-234): 4.34e-24: 100: 15.61		UBC30_ARATH (1-147): 1.96e-81: 238: 81.63
+	Hs
		895862 RFFL_HUMAN (64-236): 4.82e-24: 100: 17.78		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		896510 MIB2_HUMAN (37-234): 9.33e-29: 115: 19.34		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		896506 RFFL_HUMAN (64-236): 4.82e-24: 100: 17.78		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	At
		1277249 RGLG2_ARATH (52-234): 4.39e-27: 109: 14.05		UBC35_ARATH (4-146): 1.5e-42: 139: 49.65
+	At
		1277251 RGLG1_ARATH (52-234): 7.42e-26: 106: 13.66		UBC35_ARATH (4-146): 1.5e-42: 139: 49.65