HitPredict

Interactor 1: GBP5 (Q96PP8)
Guanylate-binding protein 5 (EC 3.6.5.-) (GBP-TA antigen) (GTP-binding protein 5) (GBP-5) (Guanine nucleotide-binding protein 5)
Gene: GBP5

Interactor 2: GBP5 (Q96PP8)
Guanylate-binding protein 5 (EC 3.6.5.-) (GBP-TA antigen) (GTP-binding protein 5) (GBP-5) (Guanine nucleotide-binding protein 5)
Gene: GBP5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 16189514, 21151871, 20180847
Identification Methods two hybrid, anti tag coimmunoprecipitation, bimolecular fluorescence complementation, two hybrid pooling approach, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GBP~GBP, GBP~GBP_C, GBP_C~GBP_C
Common GO terms GO:0000139 - Golgi membrane
GO:0002218 - activation of innate immune response
GO:0003924 - GTPase activity
GO:0004866 - endopeptidase inhibitor activity
GO:0005525 - GTP binding
and 26 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 586
Hs

1 586
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Last updated: 15 Jul 2024