Interactor 1: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Interactor 2: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 21396940, 17719543, 25527291, 26949039, 28972136, 23695783, 30021006, 30587574, 19153599, 18498246, 34294877, 35858421, 20542005, 22496338
Identification Methods enzymatic study, far western blotting
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, HECT~HECT, HECT~WW, WW~WW
Common GO terms GO:0003254 - regulation of membrane depolarization
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005771 - multivesicular body
and 32 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 975
Hs

1 975
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Last updated: 15 Jul 2024