HitPredict

Interactor 1: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Interactor 2: NFIP2 (Q9NV92)
NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413)
Gene: NDFIP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 33961781, 12050153, 19953087
Identification Methods affinity chromatography technology, enzymatic study, far western blotting, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 975
Hs

1 336
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024