HitPredict

Interactor 1: MEIS1 (O00470)
Homeobox protein Meis1
Gene: MEIS1

Interactor 2: CREB1 (P16220)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.657

The method score is based on:

Property Details
Experiments 20541704, 18160048, 20159610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, chromatin immunoprecipitation assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 390
Hs

1 327
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024