HitPredict

Interactor 1: ATAD5 (Q96QE3)
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)
Gene: ATAD5

Interactor 2: H2B1M (Q99879)
Histone H2B type 1-M (Histone H2B.e) (H2B/e)
Gene: H2BC14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1844 Hs			1 126
+	Hs
		1129840 ATAD5_HUMAN (1-1844): 0: 1306: 100.00		H2B2F_HUMAN (1-126): 2.65e-56: 173: 95.24
+	Hs
		1087352 ATAD5_HUMAN (1-1844): 0: 1306: 100.00		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		707715 ATAD5_HUMAN (1-1844): 0: 1306: 100.00		H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83
+	Hs
		918622 ATAD5_HUMAN (1-1844): 0: 1306: 100.00		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		1300359 ATAD5_HUMAN (1-1844): 0: 1306: 100.00		H2B1L_HUMAN (1-126): 4.1e-54: 167: 95.24
+	Hs
		1087196 NIPBL_HUMAN (66-837): 6.64e-54: 211: 12.10		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		918442 NIPBL_HUMAN (66-837): 6.64e-54: 211: 12.10		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		707537 RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77		H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83
+	Hs
		722208 RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		722251 RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		1129830 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B2F_HUMAN (1-126): 2.65e-56: 173: 95.24
+	Hs
		617962 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B1O_HUMAN (1-126): 3.65e-56: 172: 95.24
+	Hs
		1087299 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		1264778 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B1H_HUMAN (1-126): 6.81e-56: 171: 96.03
+	Hs
		241595 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B1K_HUMAN (1-126): 1.42e-55: 171: 96.03
+	Hs
		883041 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2BFS_HUMAN (1-126): 1.37e-55: 171: 94.44
+	Hs
		918561 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		886166 TITIN_HUMAN (17-1124): 1.43e-33: 145: 8.28		H2B1D_HUMAN (1-126): 2.86e-55: 170: 96.83
+	Sc
		355883 RFC1_YEAST (711-1292): 1.4e-34: 146: 14.55		H2B2_YEAST (3-125): 2.22e-41: 135: 69.92
+	Sc
		355471 RFC1_YEAST (711-1292): 1.4e-34: 146: 14.55		H2B1_YEAST (3-125): 3.41e-37: 124: 69.92