HitPredict

Interactor 1: MTMR9 (Q96QG7)
Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9)
Gene: MTMR9

Interactor 2: MTMR7 (Q9Y216)
Myotubularin-related protein 7 (Inositol 1,3-bisphosphate phosphatase) (EC 3.1.3.-) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
Gene: MTMR7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.981

Property	Details
Experiments	27880917, 28514442, 12890864, 25659891, 29892012, 25416956, 32296183, 33961781, 31515488, unassigned1304
Identification Methods	affinity chromatography technology, pull down, two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Myotub-related~Myotub-related
Common GO terms	GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046856 - phosphatidylinositol dephosphorylation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 549 Hs			1 660
+	Hs
		1289613 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR8_HUMAN (1-638): 0: 772: 54.62
+	Hs
		1300465 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR6_HUMAN (1-594): 0: 733: 58.33
+	Hs
		1040880 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR1_HUMAN (2-566): 0: 719: 34.21
+	Hs
		1040916 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR2_HUMAN (2-545): 0: 703: 36.89
+	Hs
		1289611 MTMR8_HUMAN (5-542): 0: 698: 34.06		MTMR8_HUMAN (1-638): 0: 772: 54.62
+	Hs
		1040859 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMR1_HUMAN (2-566): 0: 719: 34.21
+	Hs
		1040903 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMR2_HUMAN (2-545): 0: 703: 36.89
+	Hs
		1300459 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR9_HUMAN (2-547): 0: 644: 35.69
+	Hs
		1036512 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTM1_HUMAN (10-568): 0: 685: 35.25
+	Hs
		1040925 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRA_HUMAN (9-475): 5.28e-147: 447: 20.88
+	Hs
		1040909 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRD_HUMAN (134-654): 1.72e-127: 416: 21.93
+	Hs
		1040920 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRC_HUMAN (12-475): 1.92e-135: 416: 23.09
+	Hs
		1040871 MTMR1_HUMAN (5-539): 0: 712: 35.53		MTMRD_HUMAN (134-654): 1.72e-127: 416: 21.93
+	Hs
		309479 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMR5_HUMAN (133-615): 2.8e-112: 373: 22.92
+	Hs
		309478 MTMR1_HUMAN (5-539): 0: 712: 35.53		MTMR5_HUMAN (133-615): 2.8e-112: 373: 22.92
+	Hs
		59913 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRB_HUMAN (17-497): 2.66e-114: 360: 19.96