HitPredict

Interactor 1: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WW~WW
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1491 Hs			1 1116
+	Hs
		1153341 MAGI1_HUMAN (1-1491): 0: 756: 100.00		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		1300697 MAGI1_HUMAN (1-1491): 0: 756: 100.00		PKHA6_HUMAN (109-1116): 8.74e-73: 264: 28.52
+	Hs
		1199788 MAGI1_HUMAN (1-1491): 0: 756: 100.00		MAGI2_HUMAN (4-650): 6.29e-50: 195: 11.18
+	Hs
		1300696 MAGI1_HUMAN (1-1491): 0: 756: 100.00		GAB2_HUMAN (168-641): 4.97e-48: 185: 12.25
+	Hs
		1300658 MAGI1_HUMAN (1-1491): 0: 756: 100.00		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Hs
		1167407 MAGI1_HUMAN (1-1491): 0: 756: 100.00		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		1021516 DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Ce
		86408 C1P635_CAEEL (437-1435): 1.31e-43: 175: 13.86		G5EE23_CAEEL (131-787): 1.4e-67: 248: 12.82
+	Mm
		1143518 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		MAGI3_MOUSE (1-1115): 3e-83: 299: 9.62
+	Hs
		1020219 PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		1020216 PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Ce
		86389 C1P633_CAEEL (16-555): 6.2e-28: 124: 13.64		G5EE23_CAEEL (131-787): 1.4e-67: 248: 12.82
+	Ce
		88173 D3YT29_CAEEL (16-555): 3.57e-25: 115: 13.64		G5EG76_CAEEL (17-814): 1e-40: 165: 12.62
+	Mm
		1194486 DLG2_MOUSE (14-360): 2.17e-18: 93.7: 12.54		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Rn
		677809 DLG4_RAT (14-112): 2.35e-17: 90.2: 19.23		CNKR2_RAT (120-329): 4.34e-47: 185: 26.48
+	Mm
		1143379 DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Hs
		280075 MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		125652 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		ITCH_HUMAN (9-234): 1.29e-27: 123: 15.93
+	Hs
		124986 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51
+	Hs
		125703 WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39		WWP1_HUMAN (3-240): 7.83e-24: 110: 14.94