HitPredict

Interactor 1: PASK (Q96RG2)
PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)
Gene: PASK

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 24778252
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045727 - positive regulation of translation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1323 Hs			1 859
+	Hs
		1300884 PASK_HUMAN (1-1323): 0: 1887: 100.00		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		647977 MARK3_HUMAN (990-1272): 4.07e-108: 360: 33.22		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		647978 MARK3_HUMAN (990-1272): 4.07e-108: 360: 33.22		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		647963 MARK3_HUMAN (990-1272): 4.07e-108: 360: 33.22		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		647966 MARK3_HUMAN (990-1272): 4.07e-108: 360: 33.22		AGO4_HUMAN (16-859): 0: 1145: 78.51
+	Hs
		1183144 MARK2_HUMAN (989-1251): 2.4e-37: 154: 36.43		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		1183145 MARK2_HUMAN (989-1251): 2.4e-37: 154: 36.43		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1183124 MARK2_HUMAN (989-1251): 2.4e-37: 154: 36.43		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1183128 MARK2_HUMAN (989-1251): 2.4e-37: 154: 36.43		AGO4_HUMAN (16-859): 0: 1145: 78.51