Interactor 1: TR13C (Q96RJ3)
Tumor necrosis factor receptor superfamily member 13C (B-cell-activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD antigen CD268)
Gene: TNFRSF13C

Interactor 2: TN13B (Q9Y275)
Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]
Gene: TNFSF13B

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.90 0.803

The method score is based on:

Property Details
Experiments 12721620, 12755599, 12571250
Identification Methods x-ray crystallography, pull down, surface plasmon resonance
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BaffR-Tall_bind~TNF
Common GO terms GO:0005886 - plasma membrane
GO:0030890 - positive regulation of B cell proliferation
GO:0031295 - T cell costimulation
GO:0031296 - B cell costimulation
GO:0033209 - tumor necrosis factor-mediated signaling pathway
and 1 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024