HitPredict

Interactor 1: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2517 Hs			1 783
+	Hs
		1300915 CIC_HUMAN (1-2517): 0: 961: 100.00		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1271630 CIC_HUMAN (1-2517): 0: 961: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134175 CIC_HUMAN (1-2517): 0: 961: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571557 CIC_HUMAN (1-2517): 0: 961: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		818500 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		818398 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		818320 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		133924 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1344194 PRC2C_HUMAN (310-2236): 1.98e-13: 79.1: 9.20		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		571352 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Mm
		818707 SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44		DDX17_MOUSE (122-628): 3.34e-135: 417: 24.46
+	Mm
		818738 SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44		Q8BTS0_MOUSE (92-620): 1.47e-135: 416: 24.81
+	Hs
		1344172 SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		134264 PRC2C_HUMAN (310-2236): 1.98e-13: 79.1: 9.20		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1308896 SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		134254 SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571636 SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		757505 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757612 MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757803 SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23