HitPredict

Interactor 1: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Interactor 2: ING1 (Q9UK53)
Inhibitor of growth protein 1
Gene: ING1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2517 Hs			1 422
+	Hs
		1300935 CIC_HUMAN (1-2517): 0: 961: 100.00		ING2_HUMAN (158-419): 3.18e-61: 201: 51.91
+	Hs
		1059807 CIC_HUMAN (1-2517): 0: 961: 100.00		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		818586 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		ING1_HUMAN (1-422): 0: 572: 100.00
+	Hs
		727939 SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28		ING1_HUMAN (1-422): 0: 572: 100.00
+	Mm
		818768 SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44		ING5_MOUSE (158-407): 1.36e-73: 232: 34.00
+	Hs
		817983 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		BPTF_HUMAN (162-401): 2.27e-37: 147: 18.40
+	Hs
		727921 SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28		ING2_HUMAN (158-419): 3.18e-61: 201: 51.91
+	Hs
		817986 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		CHD3_HUMAN (246-406): 1.87e-24: 108: 18.79
+	Hs
		818056 SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Mm
		1142004 Q60I23_MOUSE (1102-1308): 2.84e-56: 201: 27.40		CHD4_MOUSE (246-417): 3.04e-21: 98.8: 19.89
+	Mm
		818727 SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44		CHD4_MOUSE (246-417): 3.04e-21: 98.8: 19.89
+	Ce
		1095177 EGL13_CAEEL (1033-1238): 1.27e-41: 163: 20.00		Q9XWJ8_CAEEL (245-416): 3.03e-30: 123: 27.75
+	Hs
		727856 SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28		CHD3_HUMAN (246-406): 1.87e-24: 108: 18.79
+	Hs
		727736 SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71		CHD3_HUMAN (246-406): 1.87e-24: 108: 18.79
+	Hs
		1059815 MINT_HUMAN (730-2515): 3e-28: 127: 9.45		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		1056830 MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		1018774 PRC2C_HUMAN (310-2236): 1.98e-13: 79.1: 9.20		CHD3_HUMAN (246-406): 1.87e-24: 108: 18.79
+	Hs
		1059966 PRC2C_HUMAN (310-2236): 1.98e-13: 79.1: 9.20		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		1059945 SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		1243846 KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57		CXXC1_HUMAN (333-422): 2.21e-21: 98.4: 29.79