HitPredict

Interactor 1: UIMC1 (Q96RL1)
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)
Gene: UIMC1

Interactor 2: BABA1 (Q9NWV8)
BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex)
Gene: BABAM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.55	0.722

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781, 19615732, 19261749, 19261746, 21282113, 19261748, 28569838
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006282 - regulation of DNA repair GO:0006302 - double-strand break repair GO:0007095 - mitotic G2 DNA damage checkpoint signaling and 6 others more... GO:0010212 - response to ionizing radiation GO:0016604 - nuclear body GO:0044818 - mitotic G2/M transition checkpoint GO:0045739 - positive regulation of DNA repair GO:0070531 - BRCA1-A complex GO:0140861 - DNA repair-dependent chromatin remodeling
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024