HitPredict

Interactor 1: MCCA (Q96RQ3)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)
Gene: MCCC1

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 725 Hs			1 198
+	Hs
		950686 MCCA_HUMAN (1-725): 0: 768: 100.00		ARF5_HUMAN (10-197): 5.28e-75: 225: 27.66
+	Hs
		574734 MCCA_HUMAN (1-725): 0: 768: 100.00		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		1301284 MCCA_HUMAN (1-725): 0: 768: 100.00		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		950543 MCCA_HUMAN (1-725): 0: 768: 100.00		ARF1_HUMAN (1-197): 1.8e-59: 185: 26.90
+	Hs
		398248 PCCA_HUMAN (1-715): 0: 649: 37.38		ARF5_HUMAN (10-197): 5.28e-75: 225: 27.66
+	Hs
		398222 PCCA_HUMAN (1-715): 0: 649: 37.38		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		398299 PCCA_HUMAN (1-715): 0: 649: 37.38		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		398316 PCCA_HUMAN (1-715): 0: 649: 37.38		SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00
+	Hs
		950605 ACACA_HUMAN (29-725): 0: 609: 25.40		ARF5_HUMAN (10-197): 5.28e-75: 225: 27.66
+	Hs
		574662 ACACA_HUMAN (29-725): 0: 609: 25.40		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		513564 PYC_HUMAN (47-707): 0: 601: 33.04		ARF5_HUMAN (10-197): 5.28e-75: 225: 27.66
+	Hs
		513529 PYC_HUMAN (47-707): 0: 601: 33.04		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		1024101 ACACA_HUMAN (29-725): 0: 609: 25.40		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		135983 ACACB_HUMAN (24-723): 0: 578: 26.01		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		513635 PYC_HUMAN (47-707): 0: 601: 33.04		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		1024118 ACACA_HUMAN (29-725): 0: 609: 25.40		SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00
+	Hs
		513558 PYC_HUMAN (47-707): 0: 601: 33.04		ARF3_HUMAN (8-197): 1.62e-62: 193: 27.90
+	Hs
		513652 PYC_HUMAN (47-707): 0: 601: 33.04		SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00
+	Hs
		136087 ACACB_HUMAN (24-723): 0: 578: 26.01		SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00
+	Sc
		424334 PYR1_YEAST (5-454): 1.09e-75: 268: 15.09		ARF2_YEAST (10-197): 8.45e-77: 229: 26.60