HitPredict

Interactor 1: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Interactor 2: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.884

The method score is based on:

Property Details
Experiments 30926243, 30926242, 22626734
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, enzymatic study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 12 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1077
Hs

1 1077
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024