HitPredict

Interactor 1: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Interactor 2: SENP2 (Q9HC62)
Sentrin-specific protease 2 (EC 3.4.22.-) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2)
Gene: SENP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1077 Hs			1 589
+	Hs
		1335824 UBP25_HUMAN (1-1068): 0: 977: 48.38		SENP2_HUMAN (1-589): 0: 786: 100.00
+	Hs
		1301525 UBP28_HUMAN (1-1077): 0: 1069: 100.00		SENP1_HUMAN (203-589): 3.75e-114: 355: 40.00
+	Hs
		1349829 UBP25_HUMAN (1-1068): 0: 977: 48.38		SENP1_HUMAN (203-589): 3.75e-114: 355: 40.00
+	Hs
		1297116 UBP28_HUMAN (1-1077): 0: 1069: 100.00		SENP8_HUMAN (386-571): 1.56e-45: 161: 15.98
+	Hs
		1273935 UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13		SENP1_HUMAN (203-589): 3.75e-114: 355: 40.00