Interactor 1: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Interactor 2: UBP25 (Q9UHP3)
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)
Gene: USP25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 33961781, 28514442, 19615732
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016579 - protein deubiquitination
GO:0031647 - regulation of protein stability
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1077
Hs

1 1055
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Last updated: 15 Jul 2024