HitPredict

Interactor 1: FNBP1 (Q96RU3)
Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)
Gene: FNBP1

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15252009
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 617 Hs			1 869
+	Hs
		840798 FNBP1_HUMAN (1-617): 1.21e-118: 367: 100.00		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		983403 FNBP1_HUMAN (1-617): 1.21e-118: 367: 100.00		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Hs
		840723 FBP1L_HUMAN (1-617): 4.85e-111: 347: 53.96		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		840700 CIP4_HUMAN (1-611): 2.79e-95: 306: 49.84		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Dm
		112674 M9NE16_DROME (1-610): 4.27e-86: 282: 30.08		DYN_DROME (6-861): 0: 974: 64.46
+	Hs
		840683 MYO1E_HUMAN (86-609): 3.26e-49: 186: 13.58		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		840753 FCSD1_HUMAN (7-607): 1.76e-48: 181: 12.42		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Rn
		996551 PACN1_RAT (178-607): 2.37e-36: 143: 11.86		DYN3_RAT (1-869): 0: 1079: 97.12
+	Hs
		983372 MYO1E_HUMAN (86-609): 3.26e-49: 186: 13.58		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		1142989 PACN1_MOUSE (178-607): 1.31e-36: 144: 11.86		DYN3_MOUSE (1-869): 0: 1071: 95.99
+	Ce
		760497 TOCA1_CAEEL (2-609): 2.28e-77: 259: 22.17		DYN1_CAEEL (3-815): 0: 947: 62.09
+	Mm
		760475 PACN1_MOUSE (178-607): 1.31e-36: 144: 11.86		DYN2_MOUSE (1-869): 0: 1038: 79.21
+	Hs
		840812 PACN1_HUMAN (178-607): 1.1e-35: 141: 12.09		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Mm
		760451 PACN1_MOUSE (178-607): 1.31e-36: 144: 11.86		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Hs
		983406 PACN1_HUMAN (178-607): 1.1e-35: 141: 12.09		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Rn
		599414 PACN1_RAT (178-607): 2.37e-36: 143: 11.86		DYN1_RAT (1-852): 0: 1028: 78.22
+	Hs
		840864 PACN2_HUMAN (179-607): 1.4e-23: 106: 11.26		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Mm
		760487 PACN2_MOUSE (268-607): 1.11e-22: 103: 12.43		DYN2_MOUSE (1-869): 0: 1038: 79.21
+	Hs
		983417 PACN2_HUMAN (179-607): 1.4e-23: 106: 11.26		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Dm
		649307 Q9VDI1_DROME (171-607): 2.17e-17: 87.2: 12.21		DYN_DROME (6-861): 0: 974: 64.46