HitPredict

Interactor 1: TRIB3 (Q96RU7)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B)
Gene: TRIB3

Interactor 2: TRIB3 (Q96RU7)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B)
Gene: TRIB3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34729304
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0004860 - protein kinase inhibitor activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 20 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 358
Hs

1 358
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Last updated: 15 Jul 2024