HitPredict

Interactor 1: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 790 Hs			1 543
+	Hs
		1240450 POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		792942 LIS1_HUMAN (2-284): 6.34e-64: 221: 13.91		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826772 POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821316 POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Sc
		744637 TAF5_YEAST (17-239): 5.93e-48: 184: 20.54		TCPH_YEAST (2-542): 0: 587: 62.45
+	Hs
		1306645 TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		573371 POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Sc
		744632 TAF5_YEAST (17-239): 5.93e-48: 184: 20.54		TCPE_YEAST (2-526): 0: 568: 29.98
+	Sc
		744617 TAF5_YEAST (17-239): 5.93e-48: 184: 20.54		TCPG_YEAST (2-527): 0: 546: 30.68
+	Ce
		954097 LIN53_CAEEL (119-328): 1.62e-33: 135: 22.12		Q9TZS5_CAEEL (1-541): 0: 587: 63.40
+	Sc
		791172 PFS2_YEAST (12-289): 6.3e-29: 122: 17.38		TCPH_YEAST (2-542): 0: 587: 62.45
+	Hs
		826848 TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Sc
		772894 PFS2_YEAST (12-289): 6.3e-29: 122: 17.38		TCPE_YEAST (2-526): 0: 568: 29.98
+	Hs
		821387 TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821437 NLE1_HUMAN (280-564): 1.09e-27: 119: 10.36		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573446 TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843289 POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Ce
		812717 LIN53_CAEEL (119-328): 1.62e-33: 135: 22.12		TCPB_CAEEL (5-525): 8.6e-90: 287: 34.73
+	Ce
		785433 LIN53_CAEEL (119-328): 1.62e-33: 135: 22.12		TCPA_CAEEL (15-521): 1.4e-87: 282: 35.16
+	Hs
		843357 TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79