HitPredict

Interactor 1: ELL2 (O00472)
RNA polymerase II elongation factor ELL2
Gene: ELL2

Interactor 2: EAF2 (Q96CJ1)
ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein)
Gene: EAF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	27058417, 21729782
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EAF~ELL
Common GO terms	GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0008023 - transcription elongation factor complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 640 Hs			1 260
+	Hs
		130169 ELL2_HUMAN (1-640): 0: 750: 100.00		EAF1_HUMAN (1-260): 2.01e-92: 275: 53.62
+	Hs
		876658 ELL_HUMAN (7-639): 0: 646: 45.92		EAF2_HUMAN (1-260): 1.48e-112: 326: 100.00
+	Hs
		876661 ELL_HUMAN (7-639): 0: 646: 45.92		EAF1_HUMAN (1-260): 2.01e-92: 275: 53.62
+	Hs
		1286797 ELL3_HUMAN (26-275): 2.78e-31: 128: 21.22		EAF2_HUMAN (1-260): 1.48e-112: 326: 100.00
+	Hs
		1295112 ELL3_HUMAN (26-275): 2.78e-31: 128: 21.22		EAF1_HUMAN (1-260): 2.01e-92: 275: 53.62