Interactor 1: PRPK (Q96S44)
EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase)
Gene: TP53RK
Interactor 2: TPRKB (Q9Y3C4)
EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein)
Gene: TPRKB
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16189514, 12659830, 31110156, 22912744, 26186194, 28514442, 23414517, 33961781, 32707033, 23455922, 31515488 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, two hybrid array, anti tag coimmunoprecipitation, two hybrid fragment pooling approach, tandem affinity purification, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CGI-121~Kdo |
| Common GO terms | GO:0000408 - EKC/KEOPS complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
