Interactor 1: ELL2 (O00472)
RNA polymerase II elongation factor ELL2
Gene: ELL2

Interactor 2: AFF4 (Q9UHB7)
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)
Gene: AFF4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26496610, 21729782, 26186194, 28514442, 32296183, 33961781, 22483617
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AF-4~Occludin_ELL
Common GO terms GO:0005654 - nucleoplasm
GO:0008023 - transcription elongation factor complex
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 640
Hs

1 1163
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Last updated: 15 Jul 2024