HitPredict

Interactor 1: HMGN4 (O00479)
High mobility group nucleosome-binding domain-containing protein 4 (Non-histone chromosomal protein HMG-17-like 3) (Non-histone chromosomal protein)
Gene: HMGN4

Interactor 2: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0031492 - nucleosomal DNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 369
+	Hs
		260710 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00
+	Hs
		130282 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04
+	Hs
		398960 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04
+	Hs
		130258 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06
+	Hs
		130269 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50
+	Hs
		130220 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02
+	Hs
		130250 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28
+	Hs
		398923 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79
+	Hs
		398938 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50
+	Hs
		391496 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02
+	Hs
		398810 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02
+	Hs
		398895 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57
+	Hs
		398933 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50