HitPredict

Interactor 1: HMGN4 (O00479)
High mobility group nucleosome-binding domain-containing protein 4 (Non-histone chromosomal protein HMG-17-like 3) (Non-histone chromosomal protein)
Gene: HMGN4

Interactor 2: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0031492 - nucleosomal DNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 128
+	Hs
		130258 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68
+	Hs
		130269 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48
+	Hs
		130250 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29
+	Hs
		130220 HMGN4_HUMAN (1-90): 1.56e-30: 104: 100.00		H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48
+	Hs
		398900 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43
+	Hs
		398938 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48
+	Hs
		398933 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1H_HUMAN (5-125): 2.98e-55: 170: 61.48
+	Hs
		391496 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48
+	Hs
		398810 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48
+	Hs
		398895 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A2A_HUMAN (5-125): 4.61e-55: 169: 62.30
+	Hs
		398923 HMGN2_HUMAN (1-90): 3.82e-21: 81: 86.67		H2A1C_HUMAN (5-125): 5.99e-55: 169: 61.48